Antibodies
Diagnostic & Veterinary
Supplier
Biotium
A-23187 Free Acid

SKU

59001

Size

Each

$50

Descrition & Target

A-23187, also known as Calcimycin or Calcium Ionophore III, is a calcium ionophore that rapidly equilibrates intracellular and extracellular calcium concentrations. It is commonly used for <i>in situ</i> calibrations of fluorescent calcium indicators. The ionophore allows Mn<sup>2 </sup> to enter the cells and quench intracellular fluorescence of calcium indicators.
<ul>
<li>White solid soluble in DMSO</li>
<li>Store at 4°C and protect from light</li>
<li>C<sub>29</sub>H<sub>37</sub>N<sub>3</sub>O<sub>6</sub></li>
<li>MW: 523.6</li>
<li>[52665-69-7]</li>
</ul>
Also see 4-bromo A-23187. Because 4-bromo A-23187 is nonfluorescent, it is preferred over the blue fluorescent A-23187 for calibrations of UV-excited Ca<sup>2 </sup> indicators such as Indo-1 and Fura-2 in order to keep background fluorescence to a minimum.

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